The most common side effects of GLP-1 agonists include:
Nausea.
These side effects are more likely to happen when you start the medication or if you’re taking an increased dose.
Other side effects can include:
Mild tachycardia (increased heart rate).
Infections.
Indigestion (upset stomach).
You may also have temporary mild itchiness and/or redness on your skin at the site of the injections.
Severe — but rare — side effects can include:
Acute (sudden) kidney injury.
Worsening diabetes-related retinopathy.
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