GLP-1 agonists and hypoglycemia

There’s a low risk of mild low blood sugar (hypoglycemia) episodes if you take a GLP-1 agonist. It can become a serious risk if you take GLP-1s with other medications that lower blood sugar, like sulfonylureas or insulin.

Hypoglycemia is blood sugar that’s lower than 70 mg/dL. Without proper treatment, severe hypoglycemia can be life-threatening. Hypoglycemia symptoms include:

  • Shaking or trembling.

  • Sweating and chills.

  • Dizziness or lightheadedness.

  • Weakness.

  • Faster heart rate.

  • Intense hunger (hyperphagia).

  • Difficulty thinking and concentrating.

  • Pale skin (pallor).

  • Nausea.

To treat hypoglycemia, you need to consume sugar or carbohydrates, like half a banana or half a cup of apple juice.

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